Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858408 | 0.81 | PTGIR (0.63) | PTGIR | |
| SCHEMBL9567995 | 0.75 | MCHR1 (0.40) | MCHR1USP30 | |
| SCHEMBL9567973 | 0.74 | HPGD (0.53) | TACR1MTNR1AMTNR1B | |
| SCHEMBL5633718 | 0.73 | CACNA2D1 (0.47) | TACR1TDP1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL1950916 | 0.73 | MCHR1 (0.50) | MCHR1 | |
| SCHEMBL7292707 | 0.69 | DGAT1 (0.58) | TDP1MTNR1AMTNR1B | |
| SCHEMBL30612421 | 0.69 | DGAT1 (0.58) | TDP1MTNR1AMTNR1B | |
| SCHEMBL7304447 | 0.69 | DGAT1 (0.58) | TDP1MTNR1AMTNR1B | |
| SCHEMBL3406500 | 0.69 | DGAT1 (0.58) | TDP1MTNR1AMTNR1B | |
| SCHEMBL13323480 | 0.69 | MTNR1A (0.44) | OPRD1MCHR1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |