Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622296 | 0.90 | KDM4C (0.54) | ALDH1A1KDM4CKDM5AKDM5BL3MBTL1 | |
| SCHEMBL9567996 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4CKDM5AKDM5BDHODH | |
| SCHEMBL9046402 | 0.81 | PTGIR (0.66) | ALDH1A1KDM4CKDM4E | |
| SCHEMBL9568017 | 0.78 | KCNQ2 (0.53) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL9568002 | 0.76 | MEN1 (0.49) | ALDH1A1KDM4CKDM5AKDM5BDHODH | |
| SCHEMBL5623941 | 0.76 | HTR6 (0.51) | KDM4CKDM5AKDM5BHTTTRPV1 | |
| SCHEMBL9568077 | 0.74 | TRPV1 (0.46) | ALDH1A1KDM4CKDM5AKDM5BDHODH | |
| SCHEMBL9567963 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4CKDM5AKDM5BDHODH | |
| SCHEMBL1566782 | 0.73 | SIGMAR1 (0.49) | ALDH1A1TRPV1PARP1PARP2 | |
| SCHEMBL10585088 | 0.72 | CYP19A1 (0.48) | ALDH1A1KDM4CKDM5AKDM5BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |