Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568023 | 0.92 | TRPM8 (0.48) | TRPM8HSD11B1HTTIDO1 | |
| SCHEMBL31757646 | 0.82 | MEN1 (0.39) | — | |
| SCHEMBL9567947 | 0.79 | TRPM8 (0.39) | TRPM8HSD11B1 | |
| SCHEMBL9047093 | 0.77 | TRPM8 (0.35) | TRPM8HTT | |
| SCHEMBL9046353 | 0.77 | PTGIR (0.53) | — | |
| SCHEMBL9046342 | 0.77 | PTGIR (0.38) | TRPM8 | |
| SCHEMBL7121537 | 0.75 | TRPM8 (0.46) | TRPM8HSD11B1HTTPIN1IDO1 | |
| SCHEMBL19348013 | 0.75 | HTT (0.43) | TRPM8HTT | |
| SCHEMBL17335654 | 0.73 | TRPM8 (0.44) | TRPM8HSD11B1PIN1IDO1 | |
| SCHEMBL15882481 | 0.73 | TRPM8 (0.44) | TRPM8HSD11B1PIN1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |