Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568056 | 0.86 | PTGIR (0.40) | PTGIRLMNAGAAALDH1A1KDM4E | |
| SCHEMBL9568040 | 0.74 | MCL1 (0.35) | HTT | |
| SCHEMBL9048927 | 0.74 | PTGIR (0.43) | PTGIRLMNAGAAALDH1A1KDM4E | |
| SCHEMBL9568031 | 0.73 | MEN1 (0.44) | LMNAGAAALDH1A1KDM4EHTT | |
| SCHEMBL9046416 | 0.73 | PTGIR (0.70) | PTGIR | |
| SCHEMBL9048933 | 0.71 | PTGIR (0.52) | PTGIR | |
| SCHEMBL10685924 | 0.68 | HTT (0.65) | LMNAALDH1A1KDM4ECYP2D6L3MBTL1 | |
| SCHEMBL9567959 | 0.67 | HTT (0.46) | PTGIRLMNAALDH1A1KDM4EHTT | |
| SCHEMBL1403578 | 0.66 | UGT2B17 (0.36) | KMT2A | |
| SCHEMBL9568046 | 0.65 | SMN1; SMN2 (0.32) | CYP2D6HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |