Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | UGCG | Q16739 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | PREP | P48147 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568049 | 0.90 | TBXAS1 (0.44) | SLC6A4SLC6A3UGCGALDH1A1KMT2A | |
| SCHEMBL9567978 | 0.87 | ALDH1A1 (0.46) | SLC6A4SLC6A3ALDH1A1KMT2ALMNA | |
| SCHEMBL9048134 | 0.82 | PTGIR (0.45) | SLC6A4SLC6A3UGCGALDH1A1KMT2A | |
| SCHEMBL9567956 | 0.81 | UGCG (0.48) | UGCGMTNR1AMTNR1BPREPDGAT1 | |
| SCHEMBL9568007 | 0.81 | CNR1 (0.50) | UGCGMTNR1AMTNR1BPREPPRMT5 | |
| SCHEMBL9048143 | 0.80 | PTGIR (0.70) | — | |
| SCHEMBL9048138 | 0.80 | PTGIR (0.52) | SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8713442 | 0.79 | MTNR1A (0.52) | UGCGMTNR1AMTNR1BPREPDGAT1 | |
| SCHEMBL9567998 | 0.78 | PRMT5 (0.49) | SLC6A4SLC6A3UGCGALDH1A1KMT2A | |
| SCHEMBL7292707 | 0.78 | DGAT1 (0.58) | ALDH1A1MTNR1AMTNR1BPREPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |