Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568105 | 0.91 | ITGB3 (0.43) | HPGDPOLBHTR2BHRH3ALDH1A1 | |
| SCHEMBL9568217 | 0.90 | HRH3 (0.42) | POLBL3MBTL3L3MBTL1HTR2BHRH3 | |
| Hydrochloric Acid SCHEMBL9568205 | 0.89 | HTR2B (0.39) | HPGDPOLBL3MBTL3L3MBTL1HTR2B | |
| SCHEMBL8407957 | 0.88 | POLB (0.43) | HPGDPOLBL3MBTL3HTR2BHRH3 | |
| SCHEMBL9568115 | 0.86 | SCN1A (0.46) | SCN1ASCN2ASCN3APOLBL3MBTL3 | |
| SCHEMBL9568179 | 0.85 | YAP1 (0.44) | RAB9AHTR2BSMN1; SMN2 | |
| SCHEMBL8407952 | 0.84 | ITGB3 (0.49) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9568130 | 0.82 | POLB (0.41) | POLBHTR2BHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9568137 | 0.82 | HRH3 (0.39) | HPGDPOLBHTR2BHRH3ALDH1A1 | |
| SCHEMBL9568141 | 0.82 | POLB (0.43) | HPGDPOLBHTR2BHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |