Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568105 | 0.90 | ITGB3 (0.43) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 | |
| SCHEMBL9568136 | 0.90 | SCN1A (0.43) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9568205 | 0.88 | HTR2B (0.39) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 | |
| SCHEMBL8407957 | 0.87 | POLB (0.43) | HRH3POLBALDH1A1HTR2BGAA | |
| SCHEMBL9568192 | 0.85 | PRSS1 (0.45) | HRH3CHRM2CHRM1ADRA2CCHRM3 | |
| SCHEMBL8407952 | 0.83 | ITGB3 (0.49) | POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9568179 | 0.83 | YAP1 (0.44) | HTR2BSMN1; SMN2 | |
| SCHEMBL9568130 | 0.82 | POLB (0.41) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 | |
| SCHEMBL9568137 | 0.82 | HRH3 (0.39) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 | |
| SCHEMBL9568141 | 0.81 | POLB (0.43) | HRH3POLBALDH1A1HTR2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |