Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568177 | 1.00 | MCHR1 (0.39) | MCHR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL9568230 | 0.93 | MCHR1 (0.40) | MCHR1ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL9568227 | 0.93 | MCHR1 (0.40) | MCHR1ALDH1A1GAAKMT2ATSHR | |
| SCHEMBL9568082 | 0.86 | TSHR (0.40) | MCHR1ALDH1A1GAAKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL9568148 | 0.84 | KMT2A (0.43) | ALDH1A1GAAKDM4EGLAHPGD | |
| SCHEMBL9568147 | 0.83 | ALDH1A1 (0.41) | MCHR1ALDH1A1GAATSHRDRD4 | |
| SCHEMBL9568142 | 0.83 | ALDH1A1 (0.41) | MCHR1ALDH1A1GAATSHRDRD4 | |
| SCHEMBL9568079 | 0.81 | TSHR (0.43) | MCHR1ALDH1A1GAATSHRDRD4 | |
| SCHEMBL9174514 | 0.80 | HPGDS (0.42) | ALDH1A1GAAKMT2ATSHRMAPT | |
| SCHEMBL9568102 | 0.80 | TSHR (0.39) | MCHR1ALDH1A1GAATSHRDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |