Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568156 | 0.89 | TGM2 (0.43) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL8407202 | 0.89 | YAP1 (0.49) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL9568095 | 0.86 | TGM2 (0.48) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL9568146 | 0.85 | YAP1 (0.43) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL9568145 | 0.85 | EPHX1 (0.47) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL9568160 | 0.83 | YAP1 (0.41) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL8407956 | 0.81 | ITGB3 (0.44) | POLBSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9568124 | 0.81 | ITGB3 (0.48) | SMN1; SMN2 | |
| SCHEMBL9568179 | 0.80 | YAP1 (0.44) | YAP1TGM2HTR2BHTR1AHTR1B | |
| SCHEMBL9568134 | 0.79 | YAP1 (0.39) | YAP1TGM2HTR2BHTR1AHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |