Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407202 | 0.92 | YAP1 (0.49) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568156 | 0.88 | TGM2 (0.43) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568155 | 0.87 | MEN1 (0.48) | YAP1ITGB3ITGA2BPOLBSMN1; SMN2 | |
| SCHEMBL8407952 | 0.87 | ITGB3 (0.49) | ITGB3ITGA2BPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9568146 | 0.86 | YAP1 (0.43) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568191 | 0.86 | YAP1 (0.43) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568118 | 0.84 | POLB (0.45) | ITGB3ITGA2BPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9568145 | 0.84 | EPHX1 (0.47) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568160 | 0.84 | YAP1 (0.41) | TGM2HTR2BHTR1AHTR1BHTR2A | |
| SCHEMBL9568179 | 0.82 | YAP1 (0.44) | TGM2HTR2BHTR1AHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |