Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 5/20 | 0.35 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.35 |
| ▸ | TOP1 | P11387 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568336 | 0.91 | GSK3B (0.37) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568333 | 0.90 | TOP1 (0.39) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568436 | 0.88 | PRKCZ (0.38) | — | |
| SCHEMBL9568412 | 0.87 | TOP2A (0.44) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568400 | 0.82 | LMNA (0.37) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568340 | 0.80 | MAPT (0.41) | — | |
| SCHEMBL9233250 | 0.80 | GSK3B (0.34) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568351 | 0.79 | PRKCZ (0.37) | TOP1 | |
| SCHEMBL9568342 | 0.79 | TOP1 (0.34) | GSK3BPIM1GSK3APIM3CSNK1G1 | |
| SCHEMBL9568438 | 0.78 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |