Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 9/20 | 0.39 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568328 | 0.90 | GSK3B (0.36) | TOP1KCNH2GSK3BPIM1GSK3A | |
| SCHEMBL9568351 | 0.90 | PRKCZ (0.37) | TOP1NEK1 | |
| SCHEMBL9568336 | 0.89 | GSK3B (0.37) | TOP1GSK3BPIM1GSK3APIM3 | |
| SCHEMBL9568478 | 0.88 | TOP2A (0.42) | TOP1NEK1GSK3BPIM1GSK3A | |
| SCHEMBL9568432 | 0.83 | TOP1 (0.39) | TOP1NEK1KCNH2GSK3BPIM1 | |
| SCHEMBL9568436 | 0.80 | PRKCZ (0.38) | — | |
| SCHEMBL9568346 | 0.80 | TOP1 (0.40) | TOP1NEK1KCNH2GSK3BPIM1 | |
| SCHEMBL9568340 | 0.80 | MAPT (0.41) | — | |
| SCHEMBL9568317 | 0.79 | TOP1 (0.40) | TOP1NEK1 | |
| SCHEMBL9568311 | 0.79 | TOP1 (0.41) | TOP1NEK1KCNH2GSK3BPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |