Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 9/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.34 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568311 | 0.92 | TOP1 (0.41) | TOP1NR1H2NR1H3NEK1 | |
| SCHEMBL9568346 | 0.89 | TOP1 (0.40) | TOP1NEK1 | |
| SCHEMBL9568432 | 0.87 | TOP1 (0.39) | TOP1NEK1 | |
| SCHEMBL9568467 | 0.80 | GSK3B (0.36) | TOP1 | |
| SCHEMBL9568342 | 0.80 | TOP1 (0.34) | TOP1 | |
| SCHEMBL9568385 | 0.79 | LMNA (0.35) | TOP1 | |
| SCHEMBL9568333 | 0.79 | TOP1 (0.39) | TOP1NEK1 | |
| Hydrochloric Acid SCHEMBL9568570 | 0.78 | LMNA (0.36) | TOP1 | |
| SCHEMBL9568460 | 0.78 | TOP2A (0.39) | TOP1NEK1 | |
| SCHEMBL9568358 | 0.78 | PRKCZ (0.37) | TOP1NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |