Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 8/20 | 0.53 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.48 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.48 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989706 | 0.88 | PDE7A (0.51) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL29593492 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL11144762 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL3407384 | 0.80 | TDP1 (0.58) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL11432656 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL2968510 | 0.79 | PDE7A (0.68) | ALDH1A1TDP1CYP3A4ALOX15PDE7A | |
| SCHEMBL1254184 | 0.79 | TDP1 (0.72) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL1455439 | 0.78 | PDE7A (0.74) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL11876450 | 0.78 | CA2 (0.68) | ALDH1A1TDP1CYP3A4ALOX15TSHR | |
| SCHEMBL6161726 | 0.78 | TXNRD1 (0.78) | ALDH1A1TDP1TSHRMAPK1TXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562624-A2 | Stabilization of functional proteins | Modrovich, Ivan E. (US) | 1993-09-29 | — | — | EP | disclosed |