SCHEMBL9568535

SCHEMBL9568535

C=CC(=O)Oc1ccc(S(=O)(=O)Nc2cccc3ccccc23)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.59
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
LMNA P02545 2/20 0.58
HTT P42858 1/20 0.58
ALDH1A1 P00352 4/20 0.56
MAPT P10636 2/20 0.56
METAP2 P50579 2/20 0.49
METAP1 P53582 1/20 0.49
KEAP1 Q14145 3/20 0.49
NFE2L2 Q16236 3/20 0.49
SQSTM1 Q13501 2/20 0.49
ELANE P08246 2/20 0.47
PRTN3 P24158 2/20 0.47
CHEK1 O14757 1/20 0.47
CDK8 P49336 1/20 0.47
NEK2 P51955 1/20 0.47
LIMK1 P53667 1/20 0.47
GAA P10253 2/20 0.46
HKDC1 Q2TB90 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568701 0.88 KMT2A (0.59) RECQLKMT2AMEN1LMNAHTT
SCHEMBL3272714 0.83 KMT2A (0.59) RECQLKMT2AMEN1LMNAHTT
SCHEMBL9568632 0.80 KMT2A (0.68) RECQLKMT2AMEN1LMNAHTT
SCHEMBL9568736 0.79 KMT2A (0.56) RECQLKMT2AMEN1LMNAHTT
SCHEMBL18434691 0.79 KEAP1 (0.78) RECQLKMT2AMEN1LMNAHTT
SCHEMBL29782080 0.79 KEAP1 (0.78) RECQLKMT2AMEN1LMNAHTT
SCHEMBL396803 0.78 RECQL (0.57) RECQLKMT2AMEN1LMNAHTT
SCHEMBL28519608 0.78 KEAP1 (0.67) LMNAALDH1A1MAPTKEAP1NFE2L2
SCHEMBL9568737 0.78 PGR (0.64) HTTALDH1A1
SCHEMBL9568599 0.77 PGR (0.65) KMT2AMEN1LMNAHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed