SCHEMBL9568632

SCHEMBL9568632

C=CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc3ccccc23)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.68
MEN1 O00255 3/20 0.68
LMNA P02545 1/20 0.68
HTT P42858 1/20 0.68
ALDH1A1 P00352 3/20 0.64
MAPT P10636 1/20 0.64
RECQL P46063 1/20 0.59
NAMPT P43490 1/20 0.55
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
TGM2 P21980 3/20 0.51
ALOX12 P18054 3/20 0.51
FYN P06241 1/20 0.50
SRC P12931 1/20 0.50
F13A1 P00488 1/20 0.48
TGM1 P22735 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568768 0.88 KMT2A (0.59) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL12259110 0.83 KMT2A (0.77) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL15798169 0.83 KMT2A (0.73) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL396803 0.83 RECQL (0.57) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL9568842 0.82 RECQL (0.51) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL396802 0.81 KMT2A (0.70) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL9568535 0.80 RECQL (0.59) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL29578059 0.80 KMT2A (0.72) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL340917 0.80 KMT2A (0.72) KMT2AMEN1LMNAHTTALDH1A1
SCHEMBL3820009 0.80 TGM2 (0.67) KMT2AMEN1ALDH1A1POLBTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed