Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568600 | 0.90 | CA2 (0.39) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL9325591 | 0.87 | CA2 (0.40) | LMNAALDH1A1TSHRSMN1; SMN2CA2 | |
| SCHEMBL9542131 | 0.85 | CA2 (0.41) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL29051923 | 0.84 | NR1I2 (0.43) | LMNASMN1; SMN2CA2CA1 | |
| SCHEMBL9615905 | 0.83 | LMNA (0.42) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL18636107 | 0.83 | LMNA (0.42) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL20257089 | 0.81 | CA2 (0.62) | SMN1; SMN2CA2CA1CA7CA14 | |
| SCHEMBL6266176 | 0.80 | ALDH1A1 (0.58) | LMNAALDH1A1TSHRSMN1; SMN2CA2 | |
| SCHEMBL10954373 | 0.79 | LMNA (0.38) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 | |
| SCHEMBL29024318 | 0.78 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRNT5ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |