Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9542131 | 0.93 | CA2 (0.41) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL9325591 | 0.90 | CA2 (0.40) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL9568574 | 0.90 | LMNA (0.43) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL29051923 | 0.88 | NR1I2 (0.43) | CA2CA1LMNASMN1; SMN2CA12 | |
| SCHEMBL17277069 | 0.81 | CA2 (0.43) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL11366787 | 0.79 | SMN1; SMN2 (0.57) | CA2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL9615905 | 0.77 | LMNA (0.42) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL18636107 | 0.77 | LMNA (0.42) | CA2CA1LMNAALDH1A1TSHR | |
| SCHEMBL27743429 | 0.77 | ENPP2 (0.41) | CA2CA1ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL18142228 | 0.75 | TDP1 (0.36) | LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542497-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |