Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578059 | 1.00 | KMT2A (0.72) | KMT2AMEN1HTTLMNABDKRB1 | |
| SCHEMBL12259110 | 0.86 | KMT2A (0.77) | KMT2AMEN1HTTLMNABDKRB1 | |
| SCHEMBL15798169 | 0.83 | KMT2A (0.73) | KMT2AMEN1HTTLMNABDKRB1 | |
| SCHEMBL396802 | 0.81 | KMT2A (0.70) | KMT2AMEN1HTTLMNABDKRB1 | |
| SCHEMBL904387 | 0.81 | BDKRB1 (0.53) | KMT2AMEN1HTTLMNABDKRB1 | |
| SCHEMBL9568632 | 0.80 | KMT2A (0.68) | KMT2AMEN1HTTLMNAALDH1A1 | |
| SCHEMBL28825370 | 0.80 | TSHR (0.64) | HTTALDH1A1CA12CA1CA2 | |
| SCHEMBL11641269 | 0.78 | KDM4E (0.62) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL7537943 | 0.77 | RECQL (0.76) | KMT2AMEN1HTTLMNAALDH1A1 | |
| SCHEMBL7573136 | 0.77 | KEAP1 (0.76) | KMT2AMEN1HTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| CN-101160049-B | Spiroketal-substituted cyclic ketoenols | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-05-11 | — | — | CN | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| CN-101568522-B | Trifluoromethoxyphenyl-substituted tetramic acid derivatives as pesticides and/or herbicides | BAYER CROPSCIENCE AG | 2014-05-14 | — | — | CN | claimed |
| CN-103755716-A | Spiroketal-substituted cyclic ketoenols | BAYER CROPSCIENCE AG | 2014-04-30 | — | — | CN | claimed |
| EP-1771067-B1 | SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2014-03-12 | — | — | EP | claimed |
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | claimed |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | BAYER CROPSCIENCE AG (DE) | 2006-07-20 | — | — | US | claimed |
| EP-1213966-B1 | NEW HERBICIDAL COMPOSITIONS | BAYER CROPSCIENCE LTD (GB) | 2006-04-19 | — | — | EP | claimed |
| CN-1761651-A | 2, 4-dihalo-6- (C)2－C3-alkyl) phenyl substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2006-04-19 | — | — | CN | claimed |
| EP-1383382-B1 | HERBICIDAL AGENT COMPRISING BENZOYLCYCLOHEXANEDIONES AND SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2006-03-08 | — | — | EP | claimed |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | BAYER CROPSCIENCE AG (DE) | 2005-03-10 | — | — | US | claimed |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | US | claimed |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | BAYER CROPSCIENCE K.K. (JP) | 2004-07-08 | — | — | US | claimed |
| EP-1130965-B1 | COMBINATIONS OF HERBICIDES AND SAFENERS | BAYER CROPSCIENCE GMBH (DE) | 2003-10-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166829-A1 | N-Heterocycl phenyl-substituted cyclic ketoenols | WEE1, KCNE1, CCNE1 | KMT2A 1063/4885MEN1 4715/4885HTT 2404/4885 |
| US-20040132619-A1 | Selective substituted aryl ketone and safener based herbicides | CYP2W1, CYP4Z1, CYP2E1 | KMT2A 498/4885MEN1 4229/4885HTT 846/4885 |
| US-20050009705-A1 | Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners | TARS2, TST, DDT | KMT2A 655/4885MEN1 4290/4885HTT 96/4885 |
| US-20060160703-A1 | Selective herbicides based on substituted cyclic dicarbonyl compounds and safeners | DDT, DDX41, DDC | KMT2A 547/4885MEN1 3101/4885HTT 1981/4885 |
| US-20050054535-A1 | Selective herbicides based on substituted cyclic keto-enols and safeners | DDT, LAGE3, KYAT1 | KMT2A 55/4885MEN1 4615/4885HTT 1703/4885 |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | KMT2A 1264/4885MEN1 3706/4885HTT 1973/4885 |
| US-20060160847-A1 | 2,4-Dihalogen-6-(c2-c3alkyl)-phenyl substituted tetramic acid derivatives | DDT, DDC, DAO | KMT2A 3104/4885MEN1 4548/4885HTT 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.