SCHEMBL9568646

SCHEMBL9568646

C=CC(=O)Nc1ccccc1S(=N)(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 6/20 0.47
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FGFR4 P22455 6/20 0.39
PTPN1 P18031 1/20 0.38
PTPN11 Q06124 1/20 0.38
F13A1 P00488 2/20 0.37
TGM1 P22735 2/20 0.37
RORC P51449 2/20 0.36
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
FGFR1 P11362 2/20 0.35
FGFR2 P21802 1/20 0.35
FGFR3 P22607 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29588334 0.76 TGM2 (0.50) TGM2PTPN1PTPN11F13A1TGM1
SCHEMBL1813156 0.76 TGM2 (0.50) TGM2PTPN1PTPN11F13A1TGM1
SCHEMBL9568575 0.76 KMT2A (0.44) TGM2KMT2AFGFR4RORCHTT
SCHEMBL9568663 0.76 RORC (0.42) TGM2FGFR4PTPN1PTPN11RORC
SCHEMBL964767 0.75 CA1 (0.59) TGM2CA12CA1CA2CA9
SCHEMBL29733701 0.75 CA1 (0.59) TGM2CA12CA1CA2CA9
SCHEMBL28866720 0.75 TGM2 (0.49) TGM2PTPN1PTPN11F13A1TGM1
SCHEMBL10298594 0.74 TGM2 (0.45) TGM2FGFR4PTPN1PTPN11F13A1
SCHEMBL3813620 0.74 TGM2 (0.47) TGM2PTPN1PTPN11RORCCA1
SCHEMBL29022256 0.74 TGM2 (0.47) TGM2PTPN1PTPN11F13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed