SCHEMBL9568663

SCHEMBL9568663

C=CC(=O)Nc1ccccc1S(=N)(=O)OC(C)CC

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RORC P51449 8/20 0.42
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
TGM2 P21980 2/20 0.36
FGFR4 P22455 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 1/20 0.35
EGFR P00533 2/20 0.35
EML4 Q9HC35 1/20 0.35
ALK Q9UM73 1/20 0.35
PTPN1 P18031 1/20 0.34
PTPN11 Q06124 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568575 0.79 KMT2A (0.44) RORCCA1CA2TGM2FGFR4
SCHEMBL9568666 0.77 RORC (0.42) RORCCA1CA2TGM2ALDH1A1
SCHEMBL9568646 0.76 TGM2 (0.47) RORCCA1CA2TGM2FGFR4
SCHEMBL9568826 0.73 TGM2 (0.42) RORCTGM2ALDH1A1PTPN1PTPN11
SCHEMBL9568730 0.73 RORC (0.45) RORCCA1CA2TGM2ALDH1A1
SCHEMBL9568594 0.73 ALDH1A1 (0.41) RORCCA1CA2TGM2ALDH1A1
SCHEMBL10298594 0.72 TGM2 (0.45) RORCCA1CA2TGM2FGFR4
SCHEMBL3813620 0.72 TGM2 (0.47) RORCCA1CA2TGM2PTPN1
SCHEMBL1813156 0.72 TGM2 (0.50) RORCCA1CA2TGM2LMNA
SCHEMBL29588334 0.72 TGM2 (0.50) RORCCA1CA2TGM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed