SCHEMBL9568575

SCHEMBL9568575

C=CC(=O)Nc1ccccc1S(=N)(=O)OCCCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.44
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41
RORC P51449 7/20 0.40
ALDH1A1 P00352 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TRPA1 O75762 1/20 0.37
TRPM2 O94759 1/20 0.37
PLA2G1B P04054 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
CYSLTR2 Q9NS75 1/20 0.37
CYSLTR1 Q9Y271 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662988 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28647681 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28653360 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28643614 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28926162 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28641141 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL28651793 0.83 THRA (0.47) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL9568663 0.79 RORC (0.42) RORCALDH1A1LMNACYP2C19CA1
SCHEMBL9568581 0.77 CA12 (0.56) KMT2ATHRATHRBRORCALDH1A1
SCHEMBL9568646 0.76 TGM2 (0.47) KMT2ARORCSMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed