SCHEMBL9568677

SCHEMBL9568677

C=CC(=O)Nc1cccc(NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.58
HDAC8 Q9BY41 3/20 0.55
HDAC3 O15379 2/20 0.55
HDAC4 P56524 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC7 Q8WUI4 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC10 Q969S8 2/20 0.55
HDAC11 Q96DB2 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC9 Q9UKV0 2/20 0.55
HDAC5 Q9UQL6 2/20 0.55
HTR6 P50406 3/20 0.54
IL1RN P18510 1/20 0.53
KEAP1 Q14145 1/20 0.53
ERAP1 Q9NZ08 1/20 0.53
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
GAA P10253 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568796 0.91 TGM2 (0.58) TGM2HDAC8HDAC3HDAC4HDAC1
SCHEMBL9568733 0.88 BTK (0.63) TGM2HDAC8HDAC3HDAC4HDAC1
SCHEMBL9568604 0.87 TGM2 (0.64) TGM2HDAC8HDAC3HDAC4HDAC1
SCHEMBL3820009 0.85 TGM2 (0.67) TGM2HDAC8HDAC3HDAC4HDAC1
SCHEMBL23988635 0.84 BTK (0.52) TGM2BTKALDH1A1PKM
SCHEMBL9568656 0.84 AKR1C3 (0.60) TGM2HDAC1KMT2AMEN1GAA
SCHEMBL23988608 0.83 EPHB4 (0.47) TGM2KMT2AMEN1BTKPKM
SCHEMBL23988636 0.83 EGFR (0.49) TGM2HTR6KMT2AMEN1BTK
SCHEMBL18953344 0.83 IL1RN (0.61) HDAC8HDAC3HDAC4HDAC1HDAC7
SCHEMBL12010911 0.82 MAPT (0.65) HTR6IL1RNKEAP1ERAP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed