SCHEMBL9568656

SCHEMBL9568656

C=CC(=O)Nc1cccc(S(=O)(=O)Nc2ccc3ccccc3c2)c1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.60
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
LMNA P02545 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HDAC1 Q13547 1/20 0.53
ALDH1A1 P00352 2/20 0.52
GAA P10253 1/20 0.52
PKM P14618 2/20 0.51
PKLR P30613 1/20 0.51
ATM Q13315 1/20 0.50
GPR27 Q9NS67 1/20 0.49
FYN P06241 1/20 0.48
SRC P12931 1/20 0.48
PGR P06401 1/20 0.48
MAPT P10636 1/20 0.47
PLAU P00749 2/20 0.47
TGM2 P21980 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568645 0.89 HDAC1 (0.62) AKR1C3KMT2AMEN1LMNASMN1; SMN2
SCHEMBL9568497 0.89 LMNA (0.62) AKR1C3KMT2AMEN1LMNASMN1; SMN2
SCHEMBL9568796 0.87 TGM2 (0.58) KMT2AMEN1LMNAHDAC1ALDH1A1
SCHEMBL9568677 0.84 TGM2 (0.58) KMT2AMEN1HDAC1ALDH1A1GAA
SCHEMBL31162428 0.83 FYN (0.62) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL1380888 0.83 FYN (0.62) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL397572 0.82 AKR1C3 (0.59) AKR1C3KMT2AMEN1LMNASMN1; SMN2
SCHEMBL9568768 0.82 KMT2A (0.59) KMT2AMEN1LMNASMN1; SMN2ALDH1A1
SCHEMBL397573 0.81 AKR1C3 (0.56) AKR1C3KMT2AMEN1LMNASMN1; SMN2
SCHEMBL23988608 0.80 EPHB4 (0.47) KMT2AMEN1LMNAPKMPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed