SCHEMBL9568680

SCHEMBL9568680

C=CC(=O)Nc1ccccc1S(=O)(=O)Nc1ccc2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
LMNA P02545 2/20 0.49
BCL2L1 Q07817 1/20 0.48
MCL1 Q07820 1/20 0.48
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
AKR1C3 P42330 1/20 0.46
IDH1 O75874 1/20 0.46
HDAC1 Q13547 2/20 0.46
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
GAA P10253 1/20 0.44
FYN P06241 1/20 0.44
SRC P12931 1/20 0.44
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820006 0.84 TGM2 (0.56) MAPTHPGDHTTNPSR1HDAC1
SCHEMBL14394827 0.82 IDH1 (0.49) MCL1IDH1ALDH1A1MEN1KMT2A
SCHEMBL9568497 0.82 LMNA (0.62) SMN1; SMN2LMNAMAPTHPGDAKR1C3
SCHEMBL3821671 0.82 TGM2 (0.55) SMN1; SMN2LMNAMCL1IDH1HDAC1
SCHEMBL396099 0.81 SMN1; SMN2 (0.49) SMN1; SMN2LMNABCL2L1MCL1MAPT
SCHEMBL396100 0.80 SMN1; SMN2 (0.46) SMN1; SMN2LMNABCL2L1MCL1MAPT
SCHEMBL9568842 0.80 RECQL (0.51) LMNAMCL1MAPTHTTHDAC1
SCHEMBL9568645 0.80 HDAC1 (0.62) SMN1; SMN2LMNAMAPTAKR1C3HDAC1
SCHEMBL9568656 0.79 AKR1C3 (0.60) SMN1; SMN2LMNAMAPTAKR1C3HDAC1
SCHEMBL1380888 0.78 FYN (0.62) SMN1; SMN2LMNAMAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed