SCHEMBL9568690

SCHEMBL9568690

C=CC(=O)Nc1ccc(S(=O)(=O)NC(C)CC)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 4/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
ALDH1A1 P00352 4/20 0.55
MAPT P10636 2/20 0.55
LMNA P02545 2/20 0.55
CNR1 P21554 1/20 0.55
HTT P42858 1/20 0.55
GPR55 Q9Y2T6 1/20 0.55
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
F13A1 P00488 2/20 0.48
TGM1 P22735 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA12 O43570 1/20 0.48
CA9 Q16790 1/20 0.48
CA7 P43166 1/20 0.47
CA14 Q9ULX7 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568652 0.86 TGM2 (0.65) TGM2ALDH1A1LMNAMEN1KMT2A
SCHEMBL9568603 0.85 CA1 (0.52) TGM2SMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL396211 0.83 MAPT (0.53) TGM2SMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL28230852 0.82 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1MAPTLMNACNR1
SCHEMBL396210 0.81 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1MAPTLMNACNR1
SCHEMBL9568839 0.80 TGM2 (0.65) TGM2SMN1; SMN2ALDH1A1MAPTLMNA
SCHEMBL20885095 0.80 TGM2 (0.57) TGM2SMN1; SMN2MAPTLMNAMEN1
SCHEMBL9568639 0.78 SMN1; SMN2 (0.53) SMN1; SMN2ALDH1A1MAPTLMNACNR1
SCHEMBL3813625 0.78 TGM2 (0.71) TGM2SMN1; SMN2LMNAKDM4EMEN1
SCHEMBL1688071 0.78 TGM2 (0.61) TGM2SMN1; SMN2ALDH1A1LMNAGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed