SCHEMBL9568639

SCHEMBL9568639

C=CC(=O)Oc1ccc(S(=O)(=O)NC(C)CC)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.53
POLB P06746 1/20 0.53
LMNA P02545 2/20 0.50
TP53 P04637 1/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
THRB P10828 2/20 0.48
ALDH1A1 P00352 4/20 0.47
ADAMTS4 O75173 2/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
KDM4E B2RXH2 1/20 0.45
HTT P42858 2/20 0.44
MMP9 P14780 1/20 0.44
MAPT P10636 1/20 0.44
CNR1 P21554 1/20 0.44
GPR55 Q9Y2T6 1/20 0.44
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568612 0.85 SMN1; SMN2 (0.42) SMN1; SMN2POLBLMNATP53MEN1
SCHEMBL3250222 0.83 SMN1; SMN2 (0.52) SMN1; SMN2POLBLMNATP53MEN1
SCHEMBL9568830 0.80 THRB (0.56) SMN1; SMN2LMNAMEN1KMT2ATHRB
SCHEMBL9568615 0.80 ALDH1A1 (0.52) SMN1; SMN2LMNAMEN1KMT2ATHRB
SCHEMBL9568690 0.78 TGM2 (0.58) SMN1; SMN2LMNAMEN1KMT2AALDH1A1
SCHEMBL23518077 0.78 SMN1; SMN2 (0.68) SMN1; SMN2POLBALDH1A1MMP9CA12
SCHEMBL9568741 0.78 SMN1; SMN2 (0.58) SMN1; SMN2POLBLMNATHRBALDH1A1
SCHEMBL9568797 0.78 ALDH1A1 (0.59) SMN1; SMN2POLBLMNATP53MEN1
SCHEMBL396211 0.77 MAPT (0.53) SMN1; SMN2POLBLMNAALDH1A1ADAMTS4
SCHEMBL9568766 0.76 THRB (0.55) SMN1; SMN2LMNAMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed