SCHEMBL1688071

SCHEMBL1688071

C=CC(=O)Nc1ccc(S(=O)(=O)NCCC)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 7/20 0.61
POLB P06746 1/20 0.57
LMNA P02545 4/20 0.56
GAA P10253 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
NAMPT P43490 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
F13A1 P00488 3/20 0.50
TGM1 P22735 3/20 0.50
GPR55 Q9Y2T6 1/20 0.50
ALDH1A1 P00352 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568580 0.92 TGM2 (0.58) TGM2POLBLMNAGAASMN1; SMN2
SCHEMBL9568839 0.88 TGM2 (0.65) TGM2POLBLMNASMN1; SMN2F13A1
SCHEMBL9568485 0.84 ALDH1A1 (0.50) TGM2LMNAGAASMN1; SMN2CA12
SCHEMBL9614881 0.82 POLB (0.84) POLBLMNAGAASMN1; SMN2NAMPT
SCHEMBL398016 0.81 NAMPT (0.55) TGM2LMNAGAASMN1; SMN2NAMPT
SCHEMBL3813625 0.80 TGM2 (0.71) TGM2LMNAGAASMN1; SMN2F13A1
SCHEMBL398015 0.80 POLB (0.61) POLBLMNAGAASMN1; SMN2NAMPT
SCHEMBL9568690 0.78 TGM2 (0.58) TGM2LMNASMN1; SMN2CA12CA1
SCHEMBL29277108 0.78 TGM2 (0.67) TGM2POLBLMNASMN1; SMN2CA1
SCHEMBL27403592 0.78 TGM2 (0.71) TGM2LMNACA1CA2F13A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9738064-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2017-08-22 US disclosed
US-9029066-B2 Lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2015-05-12 US disclosed
US-8978554-B2 Alkali soluble resin AGFA GRAPHICS N.V. (BE) 2015-03-17 US disclosed
US-8771918-B2 Lithographic printing plate precursor AGFA GRAPHICS N.V. (BE) 2014-07-08 US disclosed
US-20130298792-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2013-11-14 US disclosed
EP-2489512-B1 A lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2013-08-28 EP disclosed
US-20120266768-A1 Lithographic Printing Plate Precursor AGFA GRAPHICS NV (BE) 2012-10-25 US disclosed
EP-2489512-A1 A lithographic printing plate precursor Agfa Graphics N.V. (BE) 2012-08-22 EP disclosed
US-20120088191-A1 lithographic printing plate precursor AGFA GRAPHICS NV (BE) 2012-04-12 US disclosed
US-20110247516-A1 New Alkali Soluble Resin AGFA GRAPHICS NV (BE) 2011-10-13 US disclosed
WO-2011067382-A1 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2011-06-09 WO disclosed
WO-2010145947-A2 A LITHOGRAPHIC PRINTING PLATE PRECURSOR AGFA GRAPHICS NV (BE) 2010-12-23 WO disclosed
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed