SCHEMBL9568839

SCHEMBL9568839

C=CC(=O)Nc1ccc(S(=O)(=O)NCC)cc1

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 4/20 0.65
LMNA P02545 4/20 0.59
ALDH1A1 P00352 6/20 0.56
TSHR P16473 2/20 0.54
CYP2C9 P11712 1/20 0.54
POLB P06746 1/20 0.53
F13A1 P00488 2/20 0.52
TGM1 P22735 2/20 0.52
KMT2A Q03164 4/20 0.52
NPC1 O15118 1/20 0.52
MEN1 O00255 2/20 0.51
MAPT P10636 1/20 0.51
ALOX15 P16050 1/20 0.51
MAPK1 P28482 1/20 0.51
HSD17B10 Q99714 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
OPRM1 P35372 1/20 0.51
OPRD1 P41143 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1688071 0.88 TGM2 (0.61) TGM2LMNAALDH1A1CYP2C9POLB
SCHEMBL9568580 0.86 TGM2 (0.58) TGM2LMNAALDH1A1POLBKMT2A
SCHEMBL9568715 0.83 TGM2 (0.51) TGM2LMNAALDH1A1TSHRF13A1
SCHEMBL3813625 0.83 TGM2 (0.71) TGM2LMNAF13A1TGM1KMT2A
SCHEMBL4068451 0.81 POLB (0.78) LMNAALDH1A1TSHRCYP2C9POLB
SCHEMBL9568690 0.80 TGM2 (0.58) TGM2LMNAALDH1A1CYP2C9F13A1
SCHEMBL29277108 0.80 TGM2 (0.67) TGM2LMNAALDH1A1TSHRPOLB
SCHEMBL27403592 0.80 TGM2 (0.71) TGM2LMNAF13A1TGM1
SCHEMBL393582 0.79 ALDH1A1 (0.57) TGM2LMNAALDH1A1TSHRCYP2C9
SCHEMBL10405297 0.79 TGM2 (1.00) TGM2LMNAF13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
US-7232644-B2 Polymerizable composition and negative-working planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-06-19 US disclosed
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed