Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790045 | 0.80 | KMT2A (0.63) | KMT2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9568925 | 0.80 | ALDH1A1 (0.54) | KMT2AHDAC6MAPK1ALDH1A1HPGD | |
| SCHEMBL9557277 | 0.78 | MAPK1 (0.41) | KMT2AMAPK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10401793 | 0.77 | KMT2A (0.62) | KMT2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9568735 | 0.76 | MAPK1 (0.40) | KMT2AMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL9568919 | 0.75 | ALDH1A1 (0.39) | HDAC3HDAC1HDAC2HDAC6HDAC4 | |
| SCHEMBL9568853 | 0.75 | ALDH1A1 (0.65) | KMT2AMAPK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9568725 | 0.74 | POLB (0.40) | KMT2ACYP3A4MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL9568758 | 0.74 | ALDH1A1 (0.41) | KMT2AMAPK1ALDH1A1HPGDTSHR | |
| SCHEMBL9568858 | 0.74 | ALDH1A1 (0.39) | KMT2AALDH1A1NPC1RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |