Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568725 | 0.80 | POLB (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9568925 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9568841 | 0.74 | KMT2A (0.51) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| SCHEMBL9568739 | 0.73 | MAPK1 (0.37) | ALDH1A1GHSRNPSR1 | |
| SCHEMBL9568720 | 0.72 | MAPK1 (0.43) | ALDH1A1 | |
| SCHEMBL9568735 | 0.69 | MAPK1 (0.40) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9557277 | 0.69 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB | |
| SCHEMBL9568919 | 0.69 | ALDH1A1 (0.39) | ALDH1A1POLBLMNANPSR1 | |
| SCHEMBL9568758 | 0.68 | ALDH1A1 (0.41) | ALDH1A1KMT2APOLBLMNANPSR1 | |
| SCHEMBL8792691 | 0.67 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |