Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568925 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9568919 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9469451 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD11B1POLBHTT | |
| SCHEMBL9568853 | 0.81 | ALDH1A1 (0.65) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9568775 | 0.79 | NPSR1 (0.50) | ALDH1A1HPGDMAPK1MAPTTSHR | |
| SCHEMBL9568705 | 0.79 | KDM4E (0.41) | ALDH1A1HPGDMAPK1POLBHTT | |
| SCHEMBL9568708 | 0.76 | MAPK1 (0.37) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9568731 | 0.76 | MAPK1 (0.41) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9557277 | 0.76 | MAPK1 (0.41) | ALDH1A1HPGDHSD11B1MAPK1POLB | |
| SCHEMBL9568720 | 0.75 | MAPK1 (0.43) | ALDH1A1HPGDHSD11B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |