Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568705 | 0.83 | KDM4E (0.41) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL8791787 | 0.77 | ALDH1A1 (0.55) | KDM4EHPGDHSD17B10ALDH1A1KDM4C | |
| SCHEMBL8791207 | 0.75 | ALDH1A1 (0.65) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL9469451 | 0.75 | ALDH1A1 (0.62) | KDM4EHPGDALDH1A1KMT2AKDM4C | |
| SCHEMBL5966693 | 0.74 | ALDH1A1 (0.74) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL8973725 | 0.74 | ALDH1A1 (0.54) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8791016 | 0.73 | ALDH1A1 (0.52) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL8790981 | 0.72 | ALDH1A1 (0.46) | KDM4EHPGDALDH1A1TSHRMEN1 | |
| SCHEMBL9469700 | 0.72 | ALDH1A1 (0.51) | KDM4EHPGDHSD17B10ALDH1A1TSHR | |
| SCHEMBL8947261 | 0.72 | ALDH1A1 (0.75) | KDM4EHPGDHSD17B10ALDH1A1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |