Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568844 | 0.83 | KDM4E (0.51) | KDM4EHPGDHSD17B10MAPTTP53 | |
| SCHEMBL9568758 | 0.79 | ALDH1A1 (0.41) | KDM4EHPGDMAPTKMT2AALDH1A1 | |
| SCHEMBL9568925 | 0.78 | ALDH1A1 (0.54) | HPGDMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9568708 | 0.76 | MAPK1 (0.37) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL9568731 | 0.71 | MAPK1 (0.41) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL9568841 | 0.71 | KMT2A (0.51) | KDM4EHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9568853 | 0.71 | ALDH1A1 (0.65) | HPGDHSD17B10MAPTMEN1KMT2A | |
| SCHEMBL9557277 | 0.69 | MAPK1 (0.41) | KDM4EHPGDHSD17B10MAPTMEN1 | |
| SCHEMBL9568919 | 0.69 | ALDH1A1 (0.39) | KDM4EHPGDHSD17B10MAPTTP53 | |
| SCHEMBL9568725 | 0.68 | POLB (0.40) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262433-A | Antidiabetic agents | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0528277-A1 | Tetrazoleacetic acid derivatives aldose reductase inhibitors | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1993-02-24 | — | — | EP | disclosed |