Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249351 | 0.80 | HTR2A (0.42) | HTR2ACALM1BCL2BCL2L1FFAR1 | |
| SCHEMBL27597351 | 0.78 | ALDH1A1 (0.48) | BRD4CREBBPHPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL722161 | 0.75 | CALM1 (0.46) | HTR2ACALM1BCL2BCL2L1L3MBTL1 | |
| SCHEMBL1252940 | 0.75 | TSHR (0.48) | HTR2ACALM1BCL2BCL2L1FFAR1 | |
| SCHEMBL2870972 | 0.75 | CALM1 (0.46) | HTR2ACALM1BCL2BCL2L1ALOX5 | |
| SCHEMBL24612515 | 0.74 | HTR2A (0.42) | HTR2ACALM1BCL2BCL2L1L3MBTL1 | |
| SCHEMBL6045278 | 0.73 | FFAR1 (0.39) | CALM1FFAR1FFAR4MAPK14BRD4 | |
| SCHEMBL30270434 | 0.73 | CYP3A4 (0.55) | HTR2AFFAR1FFAR4MAPK14BRD4 | |
| SCHEMBL28554890 | 0.73 | LMNA (0.43) | CALM1FFAR1FFAR4MAPK14BRD4 | |
| SCHEMBL3888886 | 0.72 | CALM1 (0.50) | HTR2ACALM1FFAR1FFAR4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565450-A1 | Use of peptide derivatives for the manufacture of medicaments inhibiting endopeptidases 24.15 and 24.16 | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 1993-10-13 | — | — | EP | disclosed |