Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2656962 | 0.69 | MAPT (0.55) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL27262809 | 0.69 | PRCP (0.44) | ALDH1A1KMT2AKDM4EHPGDTSHR | |
| SCHEMBL3438533 | 0.66 | MAPT (0.50) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL8542688 | 0.66 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| Iodide SCHEMBL27302384 | 0.65 | PRCP (0.59) | KMT2AMEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2606076 | 0.64 | CHRNB2 (0.53) | POLB | |
| SCHEMBL10079150 | 0.64 | SLC6A2 (0.49) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL7678904 | 0.64 | HSD17B10 (0.42) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL27551235 | 0.64 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL27706007 | 0.63 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564129-A2 | Process for the preparation of 3-substituted-2-azetidinones | UNIVERSITY OF NOTRE DAME (US) | 1993-10-06 | — | — | EP | disclosed |
| US-5250676-A | Process for the preparation of 3-substituted-2-azetidinones | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1993-10-05 | — | — | US | disclosed |