Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282828 | 1.00 | F2 (0.56) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL7265280 | 0.84 | F2 (0.53) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL8633510 | 0.84 | F2 (0.53) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9569401 | 0.81 | F2 (0.50) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL7328756 | 0.81 | F2 (0.50) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9569393 | 0.80 | ACE (0.46) | F2HPGDFKBP1A | |
| SCHEMBL9255056 | 0.80 | ACE (0.46) | F2HPGDFKBP1A | |
| SCHEMBL9280014 | 0.78 | ALDH1A1 (0.65) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL9280010 | 0.78 | ALDH1A1 (0.65) | F2ALDH1A1CYP3A4CYP2C9PKM | |
| SCHEMBL12300145 | 0.77 | SMN1; SMN2 (0.71) | F2ALDH1A1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-A2 | N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | claimed |