Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328756 | 1.00 | F2 (0.50) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL8994630 | 0.88 | CYP3A4 (0.47) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL9569386 | 0.81 | SLC6A1 (0.41) | HPGDPOLBSMN1; SMN2 | |
| SCHEMBL7290559 | 0.81 | SLC6A1 (0.41) | HPGDPOLBSMN1; SMN2 | |
| SCHEMBL9569339 | 0.81 | F2 (0.56) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL7282828 | 0.81 | F2 (0.56) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL7265280 | 0.81 | F2 (0.53) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL8633510 | 0.81 | F2 (0.53) | F2ALDH1A1HPGDUSP2CYP3A4 | |
| SCHEMBL12300145 | 0.74 | SMN1; SMN2 (0.71) | F2ALDH1A1HPGDUSP2SCN9A | |
| SCHEMBL30239976 | 0.72 | MC4R (0.74) | F2ALDH1A1HPGDUSP2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537802-A2 | N-acylpyrrolidines and N-acylthiazolidines, process for their preparation and their use for prevention and/or treatment of amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-04-21 | — | — | EP | claimed |