Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924941 | 0.84 | CA12 (0.47) | THRBF2RL3MAPTLMNATP53 | |
| SCHEMBL11012603 | 0.84 | THRB (0.51) | THRBMAPTLMNATP53TSHR | |
| SCHEMBL24105988 | 0.82 | THRB (0.50) | THRBF2RL3MAPTLMNATP53 | |
| SCHEMBL2564592 | 0.79 | THRB (0.56) | THRBF2RL3MAPTLMNATP53 | |
| SCHEMBL24105970 | 0.79 | CA12 (0.52) | THRBF2RL3MAPTLMNATP53 | |
| SCHEMBL11011714 | 0.79 | MAPT (0.52) | THRBMAPTLMNATP53TSHR | |
| SCHEMBL84416 | 0.78 | RAB9A (0.64) | THRBMAPTLMNATP53TSHR | |
| Bromide SCHEMBL11011059 | 0.78 | MAPT (0.51) | THRBMAPTLMNATP53TSHR | |
| SCHEMBL11010261 | 0.78 | THRB (0.49) | THRBMAPTLMNATP53TSHR | |
| SCHEMBL20893213 | 0.78 | TNKS2 (0.50) | THRBMAPTLMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524055-A1 | Imidazo(2,1-b)benzothiazole-3-acetamide derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-01-20 | — | — | EP | disclosed |