Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11012079 | 0.88 | THRB (0.48) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL10814270 | 0.86 | THRB (0.48) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11011725 | 0.85 | MAPT (0.51) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11013680 | 0.81 | THRB (0.57) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL9837374 | 0.81 | RAB9A (0.53) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2564592 | 0.81 | THRB (0.56) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL10806421 | 0.81 | MAPT (0.52) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11010648 | 0.80 | MAPT (0.49) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL84416 | 0.80 | RAB9A (0.64) | THRBMAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL11012438 | 0.78 | LMNA (0.50) | THRBMAPTRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | claimed |
| US-4497817-A | ANTIALLERGENS-IMMUNOSUPPRESSIVE AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-02-05 | — | — | US | disclosed |