Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569386 | 1.00 | SLC6A1 (0.41) | SLC6A1PREPHPGDSMN1; SMN2ACE | |
| SCHEMBL8994559 | 0.88 | ACE (0.46) | PREPSMN1; SMN2ACENPC1MEN1 | |
| SCHEMBL8994560 | 0.88 | ACE (0.46) | PREPSMN1; SMN2ACENPC1MEN1 | |
| SCHEMBL9569401 | 0.81 | F2 (0.50) | HPGDSMN1; SMN2POLB | |
| SCHEMBL7328756 | 0.81 | F2 (0.50) | HPGDSMN1; SMN2POLB | |
| SCHEMBL7325895 | 0.81 | PREP (0.44) | PREPHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL9255056 | 0.81 | ACE (0.46) | HPGDSMN1; SMN2ACE | |
| SCHEMBL7325890 | 0.81 | PREP (0.44) | PREPHPGDSMN1; SMN2NPC1TDP1 | |
| SCHEMBL9569393 | 0.81 | ACE (0.46) | HPGDSMN1; SMN2ACE | |
| SCHEMBL7324911 | 0.78 | PREP (0.44) | PREPHPGDSMN1; SMN2NPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345428-A1 | Anti-amnesic pyrrolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | claimed |