Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | USP14 | P54578 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641097 | 0.87 | RORC (0.49) | RORCKDM4ETP53MAPTALDH1A1 | |
| SCHEMBL8637313 | 0.86 | RORC (0.52) | RORCKDM4ERARGTP53MAPT | |
| SCHEMBL9569710 | 0.85 | RORC (0.46) | RORCKDM4ERARGTP53MAPT | |
| SCHEMBL30626331 | 0.84 | KDM4E (0.42) | RORCKDM4ERARGTP53SCN9A | |
| SCHEMBL26074934 | 0.84 | KDM4E (0.42) | RORCKDM4ERARGTP53SCN9A | |
| SCHEMBL8636360 | 0.83 | RORC (0.46) | RORCKDM4ETP53SCN9AMAPT | |
| SCHEMBL9569701 | 0.81 | RORC (0.45) | RORCTP53MAPTALDH1A1L3MBTL1 | |
| SCHEMBL8639493 | 0.80 | CCR2 (0.45) | RORCKDM4ERARGTP53MAPT | |
| SCHEMBL30310912 | 0.80 | KMT2A (0.40) | RORCKDM4ETP53MAPTMEN1 | |
| SCHEMBL26074922 | 0.80 | KMT2A (0.40) | RORCKDM4ETP53MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696055-A | USED IN INDUCING MALE STERILITY OR PRODUCING HYBRID SEEDS IN A GRAMINEOUS PLANT | HYBRINOVA S.A. (FR) | 1997-12-09 | — | — | US | disclosed |
| EP-0363236-B1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1994-12-07 | — | — | EP | disclosed |
| US-5332716-A | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | E.I. DU PONT DE NEMOURS AND COMPANY | 1994-07-26 | — | — | US | disclosed |
| US-5129939-A | Antifertility agents | ORSAN (FR) | 1992-07-14 | — | — | US | disclosed |
| EP-0363236-A1 | Pollen suppressant comprising a 5-oxy- or amino-substituted cinnoline | HYBRINOVA (FR) | 1990-04-11 | — | — | EP | disclosed |