Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 2/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389835 | 0.78 | EGFR (0.49) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| SCHEMBL11117930 | 0.75 | TYR (0.52) | SMN1; SMN2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL9569813 | 0.74 | LMNA (0.42) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| SCHEMBL7189931 | 0.71 | CA2 (0.44) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| Trolamine SCHEMBL27926137 | 0.71 | MEN1 (0.41) | EGFRLMNAHIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL25386393 | 0.70 | TYR (0.54) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| SCHEMBL5664509 | 0.69 | LMNA (0.53) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| Trolamine SCHEMBL246804 | 0.69 | GABRA1 (0.36) | EGFRLMNAHIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4646903 | 0.69 | CA2 (0.45) | EGFRHPGDLMNAHIF1AHSD17B10 | |
| SCHEMBL29407028 | 0.69 | CA2 (0.45) | EGFRHPGDLMNAHIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524019-A1 | Hydraulic cement mixtures containing (dialkanol)aminoalkylphenols | W.R. Grace & Co.-Conn. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5102467-A | Adding a (dialkanol)aminomethyl phenol to enhance setting strength | W.R. GRACE & CO.-CONN. (US) | 1992-04-07 | — | — | US | disclosed |