Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL999411 | 0.88 | LTA4H (0.43) | LTA4HHRH3L3MBTL1PPARGPPARA | |
| SCHEMBL999410 | 0.88 | LTA4H (0.43) | LTA4HHRH3L3MBTL1PPARGPPARA | |
| SCHEMBL959991 | 0.88 | LTA4H (0.43) | LTA4HHRH3L3MBTL1PPARGPPARA | |
| SCHEMBL996213 | 0.71 | SLC6A4 (0.42) | LTA4HHRH3ALDH1A1KDM4EKMT2A | |
| SCHEMBL996214 | 0.71 | SLC6A4 (0.42) | LTA4HHRH3ALDH1A1KDM4EKMT2A | |
| SCHEMBL178468 | 0.69 | ALDH1A1 (0.53) | L3MBTL1PPARGPPARAALDH1A1GAA | |
| SCHEMBL24342044 | 0.69 | PPARG (0.52) | L3MBTL1PPARGPPARAALDH1A1GAA | |
| SCHEMBL8889857 | 0.69 | PPARG (0.49) | L3MBTL1PPARGPPARAALDH1A1GAA | |
| SCHEMBL12409058 | 0.68 | L3MBTL1 (0.66) | LTA4HHRH3L3MBTL1ALDH1A1GAA | |
| SCHEMBL11244902 | 0.68 | LTA4H (0.81) | LTA4HHRH3L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011231-A1 | 3-PHENOXYMETHYLPYRROLIDINE COMPOUNDS | THERAVANCE, INC. (US) | 2011-01-27 | — | — | WO | disclosed |