Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570545 | 1.00 | LMNA (0.46) | LMNAKMT2ATDP1HRH3GRIN2B | |
| SCHEMBL8999784 | 0.90 | MMP2 (0.45) | LMNAKMT2ATDP1HRH3GRIN2B | |
| SCHEMBL7020560 | 0.90 | MMP2 (0.45) | LMNAKMT2ATDP1HRH3GRIN2B | |
| SCHEMBL7392695 | 0.90 | MMP2 (0.45) | LMNAKMT2ATDP1HRH3GRIN2B | |
| SCHEMBL2299502 | 0.89 | NPC1 (0.46) | — | |
| SCHEMBL25357075 | 0.84 | HRH3 (0.43) | HRH3GRIN2BGRIN1EPHX2 | |
| SCHEMBL7338869 | 0.83 | MCL1 (0.47) | — | |
| SCHEMBL7338874 | 0.83 | MCL1 (0.47) | — | |
| SCHEMBL11256639 | 0.82 | LMNA (0.49) | LMNAKMT2ATDP1GRIN2BCYP3A4 | |
| SCHEMBL7346785 | 0.82 | AGTR2 (0.46) | HRH3GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573271-A1 | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1993-12-08 | — | — | EP | disclosed |