Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338869 | 1.00 | MCL1 (0.47) | MCL1AGTR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2299502 | 0.93 | NPC1 (0.46) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7346785 | 0.90 | AGTR2 (0.46) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7342093 | 0.87 | BDKRB2 (0.45) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7342091 | 0.87 | BDKRB2 (0.45) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL15241314 | 0.83 | AGTR2 (0.56) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6515997 | 0.83 | AGTR2 (0.56) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL6281354 | 0.83 | AGTR2 (0.56) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL29921 | 0.83 | AGTR2 (0.56) | AGTR2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9570545 | 0.83 | LMNA (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4316906-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1982-02-23 | — | — | US | disclosed |