Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24169276 | 0.88 | MAPT (0.57) | PLA2G2AMAPTL3MBTL1HPGDLTA4H | |
| SCHEMBL5727055 | 0.88 | MAPT (0.40) | PLA2G2AMAPTL3MBTL1HPGDLTA4H | |
| SCHEMBL11534430 | 0.82 | DAO (0.33) | NPC1RAB9A | |
| SCHEMBL6150323 | 0.80 | LTA4H (0.47) | MAPTHPGDLTA4HLMNASMN1; SMN2 | |
| SCHEMBL8844670 | 0.80 | LTA4H (0.40) | MAPTL3MBTL1LTA4HHRH3HTT | |
| SCHEMBL8534048 | 0.77 | GRIN1 (0.52) | LTA4H | |
| SCHEMBL1233605 | 0.76 | MAOB (0.40) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL10574172 | 0.76 | HPGD (0.48) | HPGDLTA4H | |
| SCHEMBL9447366 | 0.75 | POLB (0.40) | KMT2ALTA4HNPC1RAB9AHTT | |
| SCHEMBL10543991 | 0.75 | CYSLTR1 (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |