Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 14/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844776 | 0.89 | LTA4H (0.39) | LTA4HMAPTHTT | |
| SCHEMBL9570634 | 0.80 | PLA2G2A (0.46) | LTA4HL3MBTL1HRH3MAPTHTT | |
| SCHEMBL8381011 | 0.80 | GP6 (0.35) | LTA4HHRH3CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL24169276 | 0.77 | MAPT (0.57) | LTA4HL3MBTL1MAPTCYP1A2CYP2C9 | |
| SCHEMBL5727055 | 0.77 | MAPT (0.40) | LTA4HL3MBTL1MAPTHTT | |
| SCHEMBL8534048 | 0.77 | GRIN1 (0.52) | LTA4H | |
| SCHEMBL232998 | 0.74 | NR1H2 (0.46) | HRH3 | |
| SCHEMBL9978690 | 0.73 | NR1H2 (0.44) | HRH3 | |
| SCHEMBL5173931 | 0.73 | NR1H2 (0.44) | HRH3 | |
| SCHEMBL11534430 | 0.72 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643950-A | INHIBITORS OF A BACTERIAL HISTIDINE PROTEIN KINASE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |