Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727055 | 0.76 | MAPT (0.40) | HPGDLTA4H | |
| SCHEMBL9570634 | 0.76 | PLA2G2A (0.46) | HPGDLTA4H | |
| SCHEMBL10574136 | 0.75 | HPGD (0.37) | HPGDLTA4H | |
| SCHEMBL11534430 | 0.74 | DAO (0.33) | — | |
| SCHEMBL24169276 | 0.73 | MAPT (0.57) | HPGDLTA4H | |
| SCHEMBL6150323 | 0.72 | LTA4H (0.47) | HPGDLTA4H | |
| SCHEMBL5690326 | 0.72 | HRH1 (0.59) | — | |
| SCHEMBL7315817 | 0.72 | SIGMAR1 (0.56) | HPGDPARP15PARP10GRM2PARP2 | |
| SCHEMBL10254446 | 0.71 | PARP15 (0.42) | PARP15PARP10PARP2 | |
| SCHEMBL14508997 | 0.70 | PARP15 (0.55) | HPGDPARP15PARP10GRM2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845231-A | Tetrazoles and their use as hypoglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-04 | — | — | US | claimed |
| US-4845231-A | Tetrazoles and their use as hypoglycemic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |