SCHEMBL9570869

SCHEMBL9570869

COc1ccc(C(C=O)C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP2A6 P11509 1/20 0.44
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
ACP3 P15309 1/20 0.39
SLC2A1 P11166 1/20 0.38
GABBR2 O75899 1/20 0.38
GABBR1 Q9UBS5 1/20 0.38
ACHE P22303 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570578 0.82 ALDH1A3 (0.50) ALDH1A1MAPK1NPSR1KMT2A
SCHEMBL9570882 0.81 PDE2A (0.42) ALDH1A1MEN1KMT2A
SCHEMBL9570747 0.81 NQO1 (0.47) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL9570593 0.80 DRD1 (0.47) ALDH1A1L3MBTL1NPSR1MEN1RAB9A
SCHEMBL9570705 0.80 CHRM2 (0.46) ALDH1A1L3MBTL1ACHEMEN1KMT2A
SCHEMBL9570567 0.79 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL9862478 0.79 ALDH1A1 (0.42) ALDH1A1TSHRMAPK1TDP1L3MBTL1
SCHEMBL9570796 0.79 TYR (0.48) ALDH1A1MAPK1CYP2D6
SCHEMBL9570654 0.79 CYP2A6 (0.38) ALDH1A1TDP1CYP2A6CA1CA2
SCHEMBL9570646 0.78 CA12 (0.41) ALDH1A1L3MBTL1CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed